![]() Silkworm moths are significant sources of inhalant allergens, both indoors and outdoors. 4,5 The high frequency of moth as aeroallergen has been verified by skin prick test and specific serum IgE in a group of patients with asthma and allergic rhinitis. 2,3 Inhalant insect allergens are present in airborne particles and have been implicated as triggers for respiratory allergic symptoms. 1 Some of these are involved in the development of allergic diseases. There are around 150,000 species of Lepidoptera, including moths and butterflies, distributed worldwide. Future studies should be conducted to better characterize these proteins. The one at 80 kDa is the major protein, seen in all IgE-reactive patients from group 1 and in none from group 2, yet to be identified. Six major reactive proteins by immunoblot analysis from moth’s wings sensitized patients can be potential allergens. ![]() Serum samples from healthy participants did not react at all. Sera from seven out of eight patients sensitized to house dust mite demonstrated IgE-reactivity to Bombyx mori extract by Western blot analysis. All of them reacted to a protein at 80 kDa and five other proteins (66, 50, 45, 37 and 30 kDa) were identified in more than 50% of the individuals tested, considered as major allergenic proteins. ResultsĪmong the 21 participants from group 1, 19 serum samples reacted to Bombyx mori extract by Western blot. The participants were divided into 3 groups: 1) 21 allergic patients whose skin prick test was positive to Bombyx mori wing extract, 2) eight allergic patients whose skin prick test was positive to mite and negative to Bombyx mori extract 3) seven negative non-allergic subjects. Material and Methodsģ6 participants were included in an experimental study, submitted to skin prick test with Bombyx mori wing extract and six other common allergens, as well as Western blot analysis with incubated nitrocellulose membrane impregnated with silkworm moth extract and human IgE-antibody. There are no studies on adult stage of these moth species allergens involved in allergic respiratory reactions - the aim of this study. High prevalence of IgE-mediated sensitization was demonstrated in a group of patients with allergic respiratory diseases. Moths are a significant source of indoor and outdoor aeroallergens. Letters to the Editor on previously published papers are welcomed.Allergologia et Immunopathologia publishes 6 issues per year and is included in the major databases such as Pubmed, Scopus, Web of Knowledge, etc. Occasionally, the opinion of an expert on a burning topic is published in the "Point of View" The journal accepts original and review articles from all over the world, together with consensus statements from the aforementioned societies. It has and independent international Editorial Committee which submits received papers for peer-reviewing by international experts. Allergologia et Immunopathologia is the official journal of the Spanish Society of Pediatric Allergy and Clinical Immunology. Manuscripts related to clinical, epidemiological and experimental allergology and childhood immunopathology will be considered for publication. Allergologia et Immunopathologia is no longer published on Elsevier since the 2021 year.Transferred to Codon PublicationsĪllergologia et Immunopathologia is a forum for those working in the field of asthma, allergy and immunology related to childhood.
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